About the Nonprofit
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Who We Are
Rett Syndrome doesn’t stop—neither do we.
The International Rett Syndrome Foundation (IRSF) funds transformative research, empowering support, and game-changing advocacy efforts. As a results-driven nonprofit organization, we stand at the forefront of the fight to treat and cure Rett syndrome.
We are fueled by the collective effort of researchers, clinicians, parents, regional associations, advocates, and supporters to help us reach our vision of creating a world without Rett.
Our Mission
To accelerate full spectrum research to cure Rett syndrome and empower families with information, knowledge, and connectivity.
Our Vision
To create a world without Rett syndrome.
Our Promise
To be the single best opportunity to improve the lives of individuals and families living with Rett syndrome.
About
Our Story
We began in 1983 when a tight knit group of dedicated parents came together determined to improve the lives of all children with Rett syndrome. Their passion led to the first non-profit ever to focus exclusively on Rett. Now, for more than 40 years, IRSF and our legacy pioneers have invested more than $58 million to fund breakthrough discoveries and life-changing advancements in research while supporting thousands of families around the world in all stages in their Rett journey.
The International Rett Syndrome Foundation (IRSF) is a 501(c)(3) nonprofit organization based in Cincinnati, Ohio. More than half of our staff and board are parents, grandparents, or caregivers of an individual with Rett syndrome.
